Leo discovers three teen super-humans Adam, Bree and Chase, living in a secret underground lab in the high-tech home he shares with his inventor stepdad, Donald Davenport, his mom, Tasha, and Eddy, the "smart house" computer. Leo takes the trio to school, but when they are unable to contain their bionic abilities on campus, Davenport sends them away to a remote secret lab.

The trio has switched places with robot versions of themselves, sending the robots to the remote lab. Tasha is afraid of Leo's attachment to the 'robots' and convences Donald to send them to the scrap yard. Leo heads off to rescue his new friends. On their return home Donald agrees to let them stay and learn about normal human life if they and Leo can keep their bionic powers a secret.

On the Lab Rats' first day of school, all goes awry when Chase is confronted by a football player and his "Commando App" is triggered, transforming him into Spike, an unruly drill sergeant. When Spike defies the school principal, she pits the Lab Rats up against the football team to battle it out for the coveted cafeteria table

When Leo needs help asking a girl to the school dance, Adam and Chase step in to help, but the plan backfires when she falls for the wrong brother. The boys decide to settle their differences on the dance floor and each show off their best moves. Meanwhile, Bree gets to know her crush, but he gets to know her glitche

The Lab Rats get their first mission to stop Davenport's hi-tech super fast train from speeding out of control.

When Davenport's prized invention, a super strength and laser empowered exoskeleton suit, malfunctions, after Chase reverses its controls, to get back at Leo for stealing his presenting job. However, it ends up unleashing destructive power on the household, making Leo's grandma even more suspicious of the family.

When Chase refuses to admit that Adam has good ideas Adam decides to run against him for student of the semester. Meanwhile, Leo takes advantage of Bree's super speed and starts using her as his personal taxi.

When Adam, Bree and Chase forget to invite Leo to his surprise birthday party, they must make it up to him, so they take Leo into the ultra-cool virtual mission simulator and show him what it's like to be bionic.

Leo & Adam team up for the school fitness challenge expecting Adam's bionics to be his secret weapon; the plan backfires when they end up going head-to-head in the finals. Meanwhile, Bree and Chase use their bionic abilities against one another.

Leo borrows Davenport's helicopter to take Janelle on a daring date. Bree gets her own room and Adam and Chase are excited to have a room to themselves. But things get out of hand and Chase divides the room up.

Future Leo travels back in time to tell Leo, that Chase, Bree, and Adam won't make it to the future, and Leo is the only one who can save them.

Adam, Bree and Chase switch their bionics but things end up not the way they think when they can't handle it anymore.

Leo is left alone to care for the Lab Rats, but things quickly go wrong when he plays with a new gadget that glitches Adam, Bree, and Chase.

Adam, Bree and Chase learn about chores and earn allowance for the first time. To raise more money, they host a yard sale and accidentally sell an antique jewelry box that Davenport was restoring for Tasha.

Tasha takes the entire family on a nice 'tech free' beach weekend in the RV, but when Davenport discovers a solar flare headed in the Earth's direction, he secretly enlists the help of the Lab Rats.

In order to fight Trent's bullying, Leo signs up for a one-on-one basketball game against his rival.

When Leo accidentally messes up Eddy, an evil demon Teddy replaces him.

Adam, Bree, and Chase are caught on Principal Perry's surveillance camera using bionics.

Leo is blamed for breaking Marcus' guitar.

Chase accidentally discovers that he has a hidden ability - telekinesis.

Adam, Bree, and Chase sneak out to meet Marcus in Davenport’s new self-driving sports car. When Leo tries to stop them, his nemesis Marcus traps him inside the car and programs it to take him on a wild, high-speed ride bound for the bottom of the Pacific Ocean.

Leo turns to Bree for help after he mistakenly unleashes a swarm of robotic flies on the school. Adam and Chase turn their class assignment into a destructive competition.

Leo finally goes a mission as he helps Davenport and Eddy attempt to stop an underground gas leak. Adam, Bree and Chase struggle to escape from Principal Perry’s detention lockdown.

Bree is exposed to a toxic chemical sending Adam and Chase on a mission for an antidote. Bree escapes quarantine and when her side effects kick in, it's up to Leo to get her back to her capsule.

Chase and Leo enter a robot battling competition.

Adam's confidence plummets after Chase pranks him, so Chase tries to make things right by creating a fake rescue scenario, but his plan backfires and puts him in real danger.

The lab rats go on strike and express their desire to do normal teenage stuff, so Davenport recruits Leo as a "scab" rat for an upcoming demonstration.

One of Davenports inventions accidentally sucks Leo into an opposite parallel universe where Leo's the one with Bionics, Principal Perry is nice, Adam is a nerd, Chase is a Jock, and Bree is popular.

When Chase is not pictured on the yearbook, he enters a talent show to show everyone he's popular by using his bionics to move a chair with his mind. But Leo messes with Chase's bionics and he was mad so he got revenge by going into commando app and then he messes with the kids in the school which causes Davenport to turn off his bionics until he learns his lesson.

Leo follows Marcus to his secret lair (an abandoned train station) to gather evidence that proves he's bionic but ends up captured by Marcus and told that there bionics are just some dumb tricks. Meanwhile, the Lab Rats scramble to bring Tasha back before Davenport finds out that they accidentally teleported her to parts unknown.

The Lab Rats accidentally damage Davenport's one million dollar painting.

Adam gets a truck. Leo tries to get her mother out of being PTA teacher.

Davenport races Joey Logano.

The truth behind Marcus and his father.

Adam, Bree and Chase use Mr Davenport's new invention to erase moments that could land them in trouble. While, Leo causes chaos when he uses the gadget to accidentally wipe 24 years of Mr Davenport's memory, resetting him to his 15 year old self.

When Mr. Davenport invents a new freeze ray gadget, he sends the Lab Rats on a mission to Antartica to collect ice-type fuel for his invention. But when a 'category 5' storm hits Antartica, he calls the mission off. Ignoring Davenport's orders, Chase goes anyways, alone and gets trapped in an avalanche after it collapsed on him. When he tries to find a way out, he runs into Douglas along the way. Meanwhile, Leo tries to impress Janelle, but accidentally freezed her using Davenport's freeze ray gadget.

In an effort to get out of training duties, Adam enlists Leo's help to create a duplicate Adam using Davenport's experimental cloning device. However, Adam's clone uses the same device to create another duplicate to avoid going to school and the clones he creates repeat the same process resulting in a mob of ever duplicating Adams.

When the school mascot's Dingo costume is stolen by the rival team, Adam seeks revenge by taking their mascot, a llama. When Chase and Adam try to return the llama they discover that the animal has swallowed hundreds of Davenport's mechanical nanobots causing it to shoot acidic bionic spit.

When Leo discovers that his nemesis Trent is rattled about a ghostly legend at Mission Creek High, he comes up with a plan for Chase and Adam to use their bionics to stage a haunting at the school.

Principal Perry gets the idea to create a robotic version of herself.

Chase inadvertently causes Adam to shrink down to two inches.

Bree is tired of being the target of the boys' pranks.

The Lab Rats go on a rescue mission to save Dr. Evans and travel to Davenport's secret facility in the frozen tundra.

Leo and Chase use Davenport's technology to get back at Trent on the day of a big test; Bree gets exposed to a hair growth cream with bad results.

Leo and Donald escape the elevator. Principal Perry lets them stay at the school temporarily in order to get her money from Donald quicker. The Lab Rats stow away on a cargo ship to hide from the FBI and must choose to either keep quiet or help stop a submarine that will crash into the ship and risk being caught. The Lab Rats decide to stop the submarine, with Chase activating his GPS, revealing the Lab Rats' location. Douglas ends up capturing them, disguised as Donald. Douglas reveals that his new bionic partner is a billionaire named Victor Krane, who wants to destroy the Lab Rats permanently. When Donald calls the Lab Rats and tells them that Principal Perry kept their secret, they return home, only for them to get crazy as a result of the Triton App and attack the family, Leo manages to disable Chase's Triton App when he talks to him and Chase manages to disable Adam and Bree's apps. The Lab Rats and the family later see the demolition that happened to the lab and are upset.

Leo and Donald escape the elevator. Principal Perry lets them stay at the school temporarily in order to get her money from Donald quicker. The Lab Rats stow away on a cargo ship to hide from the FBI and must choose to either keep quiet or help stop a submarine that will crash into the ship and risk being caught. The Lab Rats decide to stop the submarine, with Chase activating his GPS, revealing the Lab Rats' location. Douglas ends up capturing them, disguised as Donald. Douglas reveals that his new bionic partner is a billionaire named Victor Krane, who wants to destroy the Lab Rats permanently. When Donald calls the Lab Rats and tells them that Principal Perry kept their secret, they return home, only for them to get crazy as a result of the Triton App and attack the family, Leo manages to disable Chase's Triton App when he talks to him and Chase manages to disable Adam and Bree's apps. The Lab Rats and the family later see the demolition that happened to the lab and are upset.

Since the lab is destroyed, the Lab Rats go without their capsules. This causes glitches in their bionics. In order to prevent this, Donald pulls off a huge stunt in a fiberglass jet wing he invented. Things go wrong when the jet wing runs out of fuel. Meanwhile, knowing the Lab Rats' bionic secret, Principal Perry uses Adam and Bree as her bionic servants for the day.

Since Principal Perry knows that the Lab Rats are bionic, she wants to get in the action and go on a mission with them. When they stage a fake mission and take her down to the newly built lab, things don't go as planned, and they have to save Mission Creek High from a speeding rocket. Meanwhile, Janelle goes on a date with Leo, but is beginning to see him as a jinx because she always gets hurt when he is around.

Bree gets a part-time job at a tech-support store with Caitlin, but gets out-shined by Chase while he is talking to the manager of Tech Town, Scott. Chase sees how she feels later and they agree to treat each other with respect. Meanwhile, while Tasha is away visiting Grandma Rose, Leo and Adam make a turbo zip-line instead of doing the chores that Tasha gave them, with Donald joining them later. When Tasha finds out about the zip-line, she makes the boys do the chores and she hangs out on the turbo zip-line instead, much to the dismay of Adam, Leo, and Donald.

Chase loses the phone with a bowling video of him and Adam doing bionic bowling stunts at Tech Town while working. Leo and Bree try to get Principal Perry to spend her money when she retires after Donald gives her money and Trent becomes the principal and makes Leo's life miserable. It works in the end, but Principal Perry is broke and Scott fires Caitlin after she destroys an ePhone 7, the one that had Adam and Chase's bowling stunts on it, while giving them to the customers as revenge. Leo makes Trent wear a different uniform, but to Bree and Leo's shock, he loves it, much to their dismay.

Leo invents his first high-end technological creation, a pair of attack orbs meant to protect the family, but when they can't differentiate between friend and enemy, they create more bad than good. Meanwhile, Chase steals Donald’s Eddy technology to make a Cheddy application to win a Tech Town employee contest and beat Scott, but things go wrong when the technology doesn't work as expected. Leo and Tasha go to see Janelle's play which Adam is starring in, but when Trent steals Leo's ticket, Leo and Trent ruin her play, much to Adam and Janelle's dismay.

During a lunar eclipse, Principal Perry arrives at the house to inform everyone that aliens are on the planet, much to the cha Bree, Chase, and Donald's chagrin, but Adam and Leo's shock. She insists that Chase's upset stomach is due to an alien growing inside him and chases him. However, they notice green goop leaking out of Principal Perry's ears and mouth. Donald then admits that she's an alien. Principal Perry chases everyone, while Leo records the whole thing, and eventually tires herself out. Leo accidentally wakes her and she runs off with him to the school. Adam's heat vision destroys the alien pods Principal Perry laid and Leo is freed. The mother ship beams Principal Perry away just as Donald arrives. Thinking that they will miss Principal Perry, they are sadly mistaken when the mother ship beams alien-less Principal Perry back down. It is then revealed the whole thing was Leo's entrant in a contest.

Donald shows a new motorcycle to the Lab Rats when they get a video message from Douglas that Krane has lost it and implanted himself with more bionic abilities, abilities even he doesn't know about. The Lab Rats instead believe this to be a trap, leading Donald to activate a new security system that only he can bypass. While Leo is at Mission Creek High School, Douglas arrives and tries to appeal to Leo by reminding him that he knew about Douglas and Marcus before the rest of them. Douglas then shows Leo video footage of Krane implanting himself with bionics and asks him to call his brother to prove his honesty. Back at the lab, a transmission comes in and shows Leo and Tasha captured. While Donald thinks it's Douglas, Krane reveals himself on-screen as the captor and demands that the Lab Rats arrive in 10 minutes. While the Lab Rats want to rescue them, Donald heads out alone with an extremely powerful thermal blaster. Donald arrives at Krane's lair, only for Krane to siphon the power from the blaster, rendering it useless and quickly beating Donald with super strength and molecularkinesis. During the battle, Leo and Tasha are trapped in an exothermic energy field to fry them. Afterward, Krane geo-leaps to the lab, allowing Donald to use the thermal blaster to suck in the heat to set Leo and Tasha free. As Chase works to deactivate the security system, Krane arrives and easily beats the Lab Rats with his more advanced bionics. Before Krane can finish them off, Douglas arrives and blasts Krane with a laser blaster. Although he saves the Lab Rats, Krane quickly recovers and knocks him down with another force wave. As he once again prepares to attack, Chase repels his blast back at him with a force-field, defeating him for good. Douglas plans to capture the unconscious Krane, but Donald arrives and blames the entire mess on him. Unfortunately, Krane geo-leaps out of the house and Donald demands that Douglas leaves.

Bree is accepted for a semester abroad program in Australia, but when Donald learns about it, he refuses to let her go. When Donald again refuses to let her go to a concert with her friends in favor of bionic chip maintenance, she decides she's had enough and smashes her bionic chip, much to Adam, Chase, and Donald's horror. At first, Bree relishes her new freedom and even begins bragging to a disgruntled Leo. During a mission, Bree feels helpless as Adam and Chase are gone for hours. Chase reveals that they barely made it out alive and because Bree is no longer bionic, the mission took twice as long. Bree realizes she was selfish and apologizes to Adam and Chase. She's ready to become bionic again, but Donald sadly tells her that since Douglas built the chips, he isn't sure if Bree will ever be bionic again. Meanwhile, Tasha is sick, so Leo decides to use his new pill invention on her to see if her diagnosis will reveal the problem, but when he takes some of the software from Eddy, Eddy is stuck in Tasha's body. Eddy spends the day dressing her horribly and getting her kicked out of every spot in town. Donald finally uses his nasal vacuum on Eddy and the pill is extracted. However, Eddy reveals he did a news report as Tasha, and much to her shock, he made her look like a complete buffoon.

As Donald attempts to repair Bree's damaged chip, the replacement chip keeps malfunctioning, much to Donald's frustration. Although Leo believes Douglas can help since he was the original creator, Donald refuses to even see his brother again. Realizing Donald won't change his mind, Leo finds Douglas, anyway, who reluctantly agrees to help. While Donald is away, Douglas creates a new chip as close to the original as possible, and though it seems to work, it also malfunctions by causing Bree to run uncontrollably. Donald finds Leo with Douglas at the lab, but helps out and all three manage to keep Bree still; however, they still can't find a solution. After several minutes, they finally find the error and collaborate for the first time in years, fixing Bree's chip and saving her life. Meanwhile, Adam and Chase try to find a way to replace Bree's speed. While Chase manages to power up Donald's motorcycle to go 350-400 MPH, it runs out of gas almost instantly. After Bree's chip is fixed, Donald still kicks out his brother. While watching Bree apologize for her mistake, Donald realizes everyone deserves a second chance. The next morning, Donald offers his brother a chance to move in with them temporarily, and he accepts.

Leo's scared by a shark movie, so Adam and Chase use one of Donald's sharks to scare him, but it goes haywire and Adam, Chase, Leo, and Janelle end up stuck in the house. In the end, Leo turns the sharks off. Meanwhile, Principal Perry enlists Bree and Donald's help to get into a country club, but when she lies that Donald is her husband and Bree is her daughter and they have pottery around the world, Bree must use super speed to go places without the country club owner knowing about her bionics. Eventually, Principal Perry doesn't get in after the manager figures out the lies, but she decides to spend the summer with the Davenports.

When the Lab Rats are on a mission, it is revealed that a girl was secretly recording them behind a bush. The next day, the Lab Rats go to school and everyone is looking at a viral video called The World's First Bionic Humans. They go back home to tell Donald, but he says he already knows. Meanwhile, Chase is confused that he didn't notice the girl who filmed them behind the bush, even though he thermal scanned the whole place. He then looks at a chip log and finds out that the girl was in the exact spot he scanned. Chase then goes to tell Donald, but a swarm of government agents surrounds them. Leo and Douglas are still in the lab, but they use a trap door to escape and go to school to stay safe. It is then revealed that the mission the Lab Rats were on was a setup. Krane then shows up with the girl who filmed the Lab Rats, whose name is revealed to be S-1. It is also revealed that she is bionic. Krane electrocutes Principal Perry and Douglas while S-1 crushes Leo's arm. Later, Douglas and Principal Perry help Leo to get his arm fixed and take him to the hospital. Tasha later shows up, only to realize that Leo is gone. While the Lab Rats are saying their goodbyes, Special Agent Graham tells them it's time to leave, but Adam refuses. Agent Graham orders his agents to take them down, but Adam uses his wave blast ability to knock them down. When they run to the hospital, Principal Perry tells them Krane is responsible for exposing their bionics. Meanwhile, Leo is in Douglas and Krane's old warehouse and Douglas tells him to take his bandage off and pretend to throw a ball. He then realizes that Douglas upgraded his right arm with bionics. Krane then shows up and knocks down Leo and Douglas. The Lab Rats then show up with Donald, as Krane uses a powerful bionic ability that knocks out Leo, Donald, and the Lab Rats. Krane then paralyzes Donald with his choking ability. Bree battles S-1 while Adam and Chase battle Krane, but he easily takes them down with his newly upgraded Triton App that he uses on S-1. Leo then uses his bionic arm to take down Krane. As Agent Graham arrives, Douglas reveals that Krane and S-1 are the bionic villains. Agent Graham is then saved by Bree as Krane tries to attack him and he takes Krane and S-1 into custody and locks them in a prison with a bionic signal interrupter, preventing them from using their bionics to get out. Later, the Lab Rats are at a press conference and reveal that they are bionic superhumans. While watching it, Principal Perry makes new friends with the Lab Rats. In the end, Agent Graham tells Donald he's now in charge of the Lab Rats. It is also revealed that Krane has an army of bionic soldiers, which he will use to destroy the Lab Rats.

When the Lab Rats are on a mission, it is revealed that a girl was secretly recording them behind a bush. The next day, the Lab Rats go to school and everyone is looking at a viral video called The World's First Bionic Humans. They go back home to tell Donald, but he says he already knows. Meanwhile, Chase is confused that he didn't notice the girl who filmed them behind the bush, even though he thermal scanned the whole place. He then looks at a chip log and finds out that the girl was in the exact spot he scanned. Chase then goes to tell Donald, but a swarm of government agents surrounds them. Leo and Douglas are still in the lab, but they use a trap door to escape and go to school to stay safe. It is then revealed that the mission the Lab Rats were on was a setup. Krane then shows up with the girl who filmed the Lab Rats, whose name is revealed to be S-1. It is also revealed that she is bionic. Krane electrocutes Principal Perry and Douglas while S-1 crushes Leo's arm. Later, Douglas and Principal Perry help Leo to get his arm fixed and take him to the hospital. Tasha later shows up, only to realize that Leo is gone. While the Lab Rats are saying their goodbyes, Special Agent Graham tells them it's time to leave, but Adam refuses. Agent Graham orders his agents to take them down, but Adam uses his wave blast ability to knock them down. When they run to the hospital, Principal Perry tells them Krane is responsible for exposing their bionics. Meanwhile, Leo is in Douglas and Krane's old warehouse and Douglas tells him to take his bandage off and pretend to throw a ball. He then realizes that Douglas upgraded his right arm with bionics. Krane then shows up and knocks down Leo and Douglas. The Lab Rats then show up with Donald, as Krane uses a powerful bionic ability that knocks out Leo, Donald, and the Lab Rats. Krane then paralyzes Donald with his choking ability. Bree battles S-1 while Adam and Chase battle Krane, but he easily takes them down with his newly upgraded Triton App that he uses on S-1. Leo then uses his bionic arm to take down Krane. As Agent Graham arrives, Douglas reveals that Krane and S-1 are the bionic villains. Agent Graham is then saved by Bree as Krane tries to attack him and he takes Krane and S-1 into custody and locks them in a prison with a bionic signal interrupter, preventing them from using their bionics to get out. Later, the Lab Rats are at a press conference and reveal that they are bionic superhumans. While watching it, Principal Perry makes new friends with the Lab Rats. In the end, Agent Graham tells Donald he's now in charge of the Lab Rats. It is also revealed that Krane has an army of bionic soldiers, which he will use to destroy the Lab Rats.

Leo tries to show off his bionic arm to Janelle. Meanwhile, Agent Graham promotes the Lab Rats as bionic celebrities, but when they realize they missed a mission because of him, they decide to get Donald back as their leader by pretending to have glitches in their bionics to humiliate Graham in front of the President of the United States when he comes to visit them. In the end, Donald is back as their leader after Agent Graham is fired by the president, arrested by the Secret Service, and sent to prison.

Donald and the Lab Rats attend a fan convention about the movie, Alien Gladiators. The Lab Rats queue up to meet Andre Ethier, but Caitlin comes and makes them let her cut in line in front of them, getting the lost spot and meeting Andre Ethier. They fight with Caitlin and are thrown in a security holding area with a fanboy. Meanwhile, Leo and Donald are taking part in the Fire Staff Competition to get the walk-in role in the next Alien Gladiators movie.

Chase feels that it is unfair to be picked on by Adam every time and tells Donald. Douglas overhears and unlocks a new ability for Chase, upsetting the balance in the house. Douglas tries to fix things by giving Adam a new ability as well, but Adam and Chase end up fighting with one another. Meanwhile, Bree tells Leo about a contest at Tech Town as they are about to hit their one-millionth customer and Leo competes to ride on the first anti-gravity roller coaster and meet the owner of Tech Town. Principal Perry tries to compete to crush Leo's dream. In the end, Chase and Adam have a death battle, but eventually forgive each other and find out that Douglas gave Bree the ability to go invisible, scaring everyone in the lab.

Chase gets a girl interested in him, but Adam gets jealous and tries to ruin their date by having Chase turn back into Spike. Meanwhile, Leo and Bree suspect that Principal Perry has murdered a cook from the cafeteria and Donald. They then find out it was about a hamburger truck and they misunderstood everything.

Bree wants to get revenge on Adam for embarrassing her in front of her boyfriend, Jake. Working with Chase, she puts on a cyber cloak that makes her look and sound exactly like Principal Perry and embarrasses Adam in front of the whole school. However, when she shows Adam the cyber cloak right before the dance that night, it glitches and won't come off. Bree then makes Chase wear a cyber cloak of herself and go to the dance with Jake. While that's going on, Leo and Douglas snoop in Donald's briefcase and compete for what they think is to be his new vice-president, only to find out it was for the Davenport Industries softball team. Donald then finds out that he had two cyber cloaks missing and deactivates them. This embarrasses Chase and gets Bree into trouble with Jake. She then thinks she's patched things up with Jake, but it's really Principal Perry wearing a cyber cloak.

During Christmas, when the Lab Rats discover that their new action figures are being outsold by another toy, The Nerble, they attempt to improve their toys by adding special features. After adding them they decide that the toys are too dangerous for kids and put them in a box to be destroyed. Tasha is running a toy drive at the school and is collecting gifts. She finds the action figures and hands them out. When the Lab Rats find out, they rush to school and try to catch the action figures. After destroying the toy drive, they find a way to make it up to Tasha and the kids. Leo and Donald have a snowball fight in the house and Grandma Rose shows up just as Leo uses his bionic arm. Rose gets mad and calls Donald a bad father. Donald tries to makes it up to Rose by giving her a Bree action figure, but it promptly explodes.

The Lab Rats plan to gain good publicity by having cameramen film them during a mission, but it turns into a disaster when they fight for screen time. After the mission, the president orders the team to stay away from the public in order to let him settle things down. However, it goes wrong when Leo and Principal Perry are holding back angry protesters who want the Lab Rats gone, and Leo accidentally uses his bionic arm. As the protesters become even more enraged, they try to storm the house; Adam panics and uses his bionic super breath to blow everyone off the premises. However, Chase criticizes Adam's actions and the Lab Rats start fighting. They eventually decide to break the team. Three weeks later, the Lab Rats refuse to talk to each other, but they are forced into action when Krane plans to use his Triton App on everyone in the world. A large battle ensues, pitting Leo, Donald, Douglas, and the Lab Rats against Krane and his bionic army. Most of the soldiers attack Adam and Bree, who manage to take them out. Chase has a one-on-one battle with S-3 and Leo has one-on-one battle against S-1. Donald and Douglas attack the soldiers surrounding the satellite, but Krane keeps them from getting too close. Eventually, the Lab Rats and the rest of the team manage to hold back many of the soldiers, but they are running out of time to stop Krane. Douglas then reveals that the Lab Rats can fuse their abilities to stop Krane. They succeed, blasting Krane into the sky and breaking his control over the soldiers. However, their victory is cut short when they find out that Donald is in serious condition after the battle. Later they find out that after the surgery, Donald is still in a very delicate condition. Leo is made an official member of the Lab Rats and gets an upgrade to his bionic arm.

The Lab Rats plan to gain good publicity by having cameramen film them during a mission, but it turns into a disaster when they fight for screen time. After the mission, the president orders the team to stay away from the public in order to let him settle things down. However, it goes wrong when Leo and Principal Perry are holding back angry protesters who want the Lab Rats gone, and Leo accidentally uses his bionic arm. As the protesters become even more enraged, they try to storm the house; Adam panics and uses his bionic super breath to blow everyone off the premises. However, Chase criticizes Adam's actions and the Lab Rats start fighting. They eventually decide to break the team. Three weeks later, the Lab Rats refuse to talk to each other, but they are forced into action when Krane plans to use his Triton App on everyone in the world. A large battle ensues, pitting Leo, Donald, Douglas, and the Lab Rats against Krane and his bionic army. Most of the soldiers attack Adam and Bree, who manage to take them out. Chase has a one-on-one battle with S-3 and Leo has one-on-one battle against S-1. Donald and Douglas attack the soldiers surrounding the satellite, but Krane keeps them from getting too close. Eventually, the Lab Rats and the rest of the team manage to hold back many of the soldiers, but they are running out of time to stop Krane. Douglas then reveals that the Lab Rats can fuse their abilities to stop Krane. They succeed, blasting Krane into the sky and breaking his control over the soldiers. However, their victory is cut short when they find out that Donald is in serious condition after the battle. Later they find out that after the surgery, Donald is still in a very delicate condition. Leo is made an official member of the Lab Rats and gets an upgrade to his bionic arm.

Donald is in critical condition after the battle with Krane and his soldiers; Leo visits him in the hospital and in an attempt to save him, he risks his life to perform a dangerous bionic process, accelerating his aging process, thus turning him into an old man. Meanwhile, after being deactivated from the Triton App, Krane’s former bionic soldiers have nowhere to go and follow Adam home. The Lab Rats try to protect them because they aren't evil anymore. However, the president doesn't get this and tries to have them arrested, but changes his mind when the soldiers use their powers to heal and save Leo who almost died of old age. Right when they are going to be taken into custody, a newly healed Donald strikes up a deal with the president to build an academy for the soldiers.

Leo finds out that he will be a student at the bionic academy, not a mentor like Adam, Bree and Chase. Chase engages in a battle against a former nemesis and Adam mentors a younger student.

Donald leaves the Lab Rats in charge of the bionic academy while he celebrates his anniversary with Tasha. Leo invites Janelle to the island, but gets distracted by his nemesis, Spin. Spin challenges Leo to a bionic battle. Meanwhile, Adam tells Bob to do all the things he can't do when Donald is around. Bob goes ahead and steals Donald's plane, but he then hits a button that deactivates the auto-pilot. Sebastian and the Lab Rats work together to save Bob. Back at the bionic battle, Leo tries to impress Janelle by battling with Spin. Spin gets the first attack and knocks Leo over. Leo then fights back and hits Spin in the leg. Janelle rushes over to Spin, who is crying, and helps him up. Janelle gets upset at Leo and takes Spin to get a smoothie. It is then revealed that Spin faked the injury so Janelle would spend time with him. Leo tries to prove that Spin is faking it by taking his crutches. Janelle then yells at Leo and carries Spin away. Leo tries again by filming Spin admitting faking the injury, but Spin then smashes Leo's tablet. Janelle walks in and yells at Leo and Spin. Leo and Spin then become her servants and they must give her the vacation that she deserves. Later, Adam uses Donald's jet wing to fly up to the jet and save Bob. When Adam tries re-activating the auto-pilot, the plane begins to fall. Adam helps Bob conquer his fear of heights by jumping out of the jet. Bob takes Adam's parachute and Adam jumps out to try to get it from Bob. At Donald's house, just as Donald finishes setting up the table, Adam and Bob fall through the ceiling. Donald is disappointed with the Lab Rats. Adam confesses and tells him that he wasn't a good mentor. Bob tells Donald that Adam was a good mentor by boosting his confidence. Donald then tells him that his plane was a smart plane that even without the auto-pilot the plane would land itself automatically.

Sebastian has secretly formed an evil rebellion to get revenge on the Lab Rats for destroying his father. Meanwhile, Leo is trapped with the other bionic people who also want revenge, but Leo manages to convince Spin and Bob to help him, and, in the end, Sebastian is defeated, his rebellion is brought down, and he and his comrades are taken to a facility. Meanwhile, Donald successfully convinces the others that he has the best interest for them at heart while Adam still blames Chase for everything that happened after the rebellion is over.

Sebastian has secretly formed an evil rebellion to get revenge on the Lab Rats for destroying his father. Meanwhile, Leo is trapped with the other bionic people who also want revenge, but Leo manages to convince Spin and Bob to help him, and, in the end, Sebastian is defeated, his rebellion is brought down, and he and his comrades are taken to a facility. Meanwhile, Donald successfully convinces the others that he has the best interest for them at heart while Adam still blames Chase for everything that happened after the rebellion is over.

After sneaking some students off the island and to the mainland, the Lab Rats accidentally leave Spin and Bob behind and must retrieve them before Donald finds out. Meanwhile, Donald tries on Chase's mission suit and he and Leo scramble to get it off before Chase gets home.

When suspicious events happen overnight on the bionic island, everyone is convinced a new threat has emerged. However, this threat is revealed to be Leo, when his bionics glitch because Douglas never gave Leo a capsule.

Adam brings a dog back to the island and Douglas reveals that it's his old dog, Otis, who Douglas made bionic in order to save his life when Otis was injured. Chase turns out to be allergic to dogs as he starts sneezing, so Douglas says that Otis has to leave, but he and Adam actually hide the dog. Meanwhile, Leo gets a new smartphone application assistant named Shelly, with whom he has fallen in love.

The Lab Rats are on a mission to save people from a wildfire; when the people start to chant Adam, Bree, and Chase's names, Leo gets jealous and wants to become known. Douglas gets put in charge to develop a new technology for the academy, but can only come up with things that can hurt the students.

Adam and Chase each lead their own student groups against each other in a series of simulated exercises that will evaluate both student and mentor performance. However, after Chase's group fails at defeating the exoskeleton and defusing a virtual bomb, Chase decides to find a way to cheat and win.

When Leo is injured during a mission, Tasha rushes to the academy to take care of him. After finding out what happens on missions, she bans Leo from joining any more missions, but he disobeys her and goes on a mission with the rest of the team. When Tasha finds out, she kicks Leo off the team and tells him that he is moving back to Mission Creek.

Chase and Douglas reanimate a prehistoric sea spider. It escapes and bites Adam, which poisons him. It then grows and becomes 50 feet long due to growth hormones that had been given to it by Douglas. Everyone tries to stop the spider so they can create a cure for Adam.

Douglas finds out that there is a student named Kate with the Commando App. Chase tries to activate her Commando App, named Spikette by Douglas, so he can research her. When he starts fighting with Adam, she activates her Commando App and thinks Chase is her baby. While she destroys the bionic academy, Bree forces Chase to activate his Commando App by embarrassing him so he and Kate can battle. Unfortunately, he teams up with her. Douglas gives Bree a Commando App and she and Kate begin battling each other. Bree wins and Douglas extracts Kate's chip. Chase apologizes to Kate and finds out that Douglas replaced her Commando App with sonic screaming.

Chase and Donald have invented a new technology that takes in energy from any environment. Chase feels that he does not get his share of spotlight when Donald sells the product without his approval. Meanwhile, Kaz comes to the bionic academy to get powers, bringing Oliver with him.

Donald's top scientist, Dr. Ryan, arrives to test Chase's invention. The two of them dislike each other and don't get along. When Donald puts Dr. Ryan in charge of the space elevator, Chase immediately gets jealous. Donald then makes Chase Dr. Ryan's assistant. Dr. Ryan puts Chase in charge of screwing in the lug nuts, but Chase refuses, and Dr. Ryan builds the space elevator without Chase. The day of the launch, Chase performs a bionic scan of the elevator and finds a major braking flaw on the elevator.

Douglas tells the group that his old college ex-girlfriend, a film director named Giselle, will be making a film titled Bionic Action Hero based on all of them and starring an up-and-coming actor named Troy West. Giselle and Troy visit the island to learn about the bionic team.

Douglas tells the group that his old college ex-girlfriend, a film director named Giselle, will be making a film titled Bionic Action Hero based on all of them and starring an up-and-coming actor named Troy West. Giselle and Troy visit the island to learn about the bionic team.

Adam, Bree, and Chase are looking for Leo because he is late for training and find out he is in Mission Creek because Janelle threatened to break up with him. S-1 shows up unexpectedly and shocks everyone. She came to the island because, like everyone else, her memory is blank, but has continuing flashbacks of Krane.

Douglas creates a device that makes any bionic human as smart as Chase. After Douglas tests it on Bob, Bob starts spending time with Chase. This leaves Adam in envy. Meanwhile, Perry made the island officially her own, which makes Bree and Leo angry at her.

Donald gives Eddy a human body and replaces his disrespectful personality to make him nicer. Perry restores his old personality, and he attempts to harm the students.

Leo just finishes his movie marathon while everyone else is frustrated because they have nothing to do on Halloween. Bob intentionally stays behind while the other students are away with Davenport to a museum. Perry says she's going to another island across from theirs, but Douglas says no because it's deserted and has been uninhabited for years. When Douglas leaves, the group decides to go anyway.

Donald tells the group that the president has decided to host an award ceremony because they have completed their one-thousandth mission and Leo wants his recognition, but it's only for the original members. Disappointed, Leo forms his own team with S-1, who calls herself Taylor now, and Logan.

Tasha arrives on the Bionic Island informing everyone that she has tickets to a big football game of the Pioneers (mascot of a college that she went to) vs Vikings (mascot of a college that Perry went to) and Perry arrives stating that she has been trying to score tickets for weeks but it was sold out. When she asks Tasha if she has any tickets, Tasha lies saying that she hasn't. When they are about to enter the game, Perry eventually finds out the truth, she becomes furious and destroys the tickets which causes Leo, Donald, and Tasha to try to get new tickets competing against her in The Ultimate Tailgate Challenge, hosted by NFL former linebacker Willie McGinest. Meanwhile, Bree attempts to achieve her college experience by fitting in with a couple of college students (who are football fans) and attempting to use her bionics to impress them.

Everyone is shocked when Douglas introduces a fourth bionic sibling named Daniel who’s been living a normal life with an adopted family. Daniel later comes to the academy to meet his father, uncle, and cousins. After Daniel's bionics are accidentally activated by the Lab Rats, Donald and Douglas find out what happened they have to come clean to Daniel about his power-replicating abilities. Daniel also finds out that his cousins are actually his biologic siblings. Filled with anger, Daniel goes out for air on the beach, where Leo and him have a conversation about Douglas. Not too long after, Daniel, using Leo's abilities, accidentally causes a leak in the hydro-loop's fuel tank. After Adam and Daniel combined their powers to stop it, Douglas apologizes to Daniel for lying and Daniel decides to give Douglas a second chance.

In the middle of a massive heat wave, the whole family is going to space to see Donald's space colony, called "Davenportia". Adam annoys Chase while Chase tries to give his safety instructions and accidentally blasts them into space. After leaving the solar system, they initiate hyper-speed and land on the planet Lithios. In the dome, it's discovered that Perry sneaked her way in with the rest of the colonists.

Donald and Douglas reveal that they have built an upgrade for all the students bionics, except for Leo's. But the upgrade doesn't work on Adam, Bree, and Chase because their systems are older. Adam, Bree, and Chase are therefore left at their level, while all the students are much more powerful. Meanwhile, Daniel is brought to the Academy because he had been using his bionics in the outside world. Douglas decides to enroll Daniel at the Academy, and he makes Leo his mentor. Leo steadily tries to teach Daniel, but Daniel proves to be unteachable, so Leo gives him the upgrade as well. The students steadily start to vanish, including Daniel. Giselle Vickers, Douglas' old girlfriend, is revealed to have captured them. Daniel sends a video message to the Island, requesting help.

Giselle reveals she dug up Marcus from Douglas' old lair and rebuilt him, piece-by-piece. Marcus wants revenge on Douglas for leaving him to die. Everyone rushes Giselle and Marcus, but Marcus knocks everyone unconscious. Donald and Douglas are tied together in chairs, while Adam, Bree, Chase, and Leo are put in the chamber with the students, while Daniel is pulled out.