Larry discusses the backlash over the Oscar nominations' lack of diversity and the success of recent protests with Cory Booker, Talib Kweli, Bill Burr, and Shenaz Treasury.

Larry takes an unflinching look at the sexual assault allegations against Bill Cosby with panelists Jamilah Lemieux, Kathleen Madigan, Baratunde Thurston and Keith Robinson.

Larry discusses the 2015 State of the Union address as well as the image and legacy of President Obama with panelists Jon Lovett, David Remnick, Amy Holmes, and Godfrey.

Larry discusses the changing state of U.S.-Cuba relations with panelists John Leguizamo, Soledad O'Brien, Mauricio Claver-Carone and Mike Yard.

Larry takes a look at the controversy swirling around the movie "American Sniper" with panelists Matt Taibbi, Paul Rieckhoff, Sabrina Jalees and Nick Irving.

Larry talks about the Disneyland measles epidemic and the fight against vaccines with panelists Holly Phillips, Judy Gold, Zoey O'Toole and Mike Yard.

Larry discusses the Koch brothers and the flood of private money in political campaigns with panelists Zephyr Teachout, David Webb, Hari Kondabolu and Ted Alexandro.

Larry tackles the Deflategate scandal and dishonesty in professional sports with panelists Jake Tapper, Katie Nolan, Sherrod Small and Seaton Smith.

Larry addresses America's obesity problem with panelists Morgan Spurlock, Marianne Kirby, Lavell Crawford and Shannon DeVido.

Panelists Lance Bass, Sally Kohn, Jessica Kirson and Michel Faulkner join Larry to talk about America's growing acceptance of same-sex marriage.

Panelists Common, Charles Blow, Joe Jones and Mike Yard join Larry for an in-depth discussion of African-American fatherhood.

Larry addresses the debate over genetically engineered babies with panelists Gabrielle Union, Penn Jillette, Holly Phillips and Rachel Feinstein.

Panelists Michael McKean, Kimberly Dozier, Negin Farsad and Wes Moore join Larry for a discussion about ISIS as well as the U.S.'s foggy relationship with war.

Panelists Retta, Anne-Marie Johnson, Deborah Tillman and Pete Dominick discuss free-range parenting, government overreach and child discipline.

Larry tackles viewers' questions about the anti-vaccine movement, obesity and beauty standards with Anthony Anderson, S.E. Cupp, Michaela Pereira and Rory Albanese.

Panelists Martin Short, Frank Rich, Big Sean and Tara Setmayer weigh in on Rudy Giuliani's claim that President Obama doesn't love America.

Larry talks Islamophobia and Muslim extremism with panelists Ahmed Shihab-Eldin, Dean Obeidallah, Reggie Love and Shenaz Treasury.

Larry talks about the significance of the proposed Mars One expedition with Don Cheadle, Sonia Van Meter, Ricky Velez and Lee Daniels.

Issa Rae, Christina Greer, Jacque Reid and Marina Franklin join Larry to discuss issues black women face in the workplace as well as the pros and cons of interracial dating.

New York City Mayor Bill de Blasio sits down with Larry to discuss income inequality, police-community relations and the city's marijuana laws.

Joy Reid, Bonnie McFarlane, Megan Powers and Emma Iannini join Larry for a debate about legalizing guns on college campuses.

Adam Carolla, Carl Hart, Roland Martin and Michelle Buteau join Larry to talk about the growing acceptance of legalizing marijuana in the U.S.

Sunny Hostin, Phillip Agnew, Michael Skolnik and Godfrey discuss the disturbing findings from a Department of Justice's report on the Ferguson, MO, police department.

Cedric the Entertainer, Daymond John, Ted Alexandro and Maria Hinojosa discuss the Apple Watch and the ethical issues faced by consumers of modern technology.

Larry reacts to an Oklahoma fraternity's racist chant and discusses equal opportunity for women with panelists Alicia Menendez, Egypt Sherrod, Chloe Hilliard and Jim Norton.

American gun owners shoot their penises off at an alarming rate, and Larry examines Jeb Bush's comments about black voters with DeRay Mckesson, Mike Yard and Rory Albanese.

President Obama and Vladimir Putin face off at the U.N. summit, and Larry discusses the discovery of water on Mars with Bill Nye, Michelle Buteau and Ricky Velez.

Congressional Republicans attack Planned Parenthood President Cecile Richards, and Larry discusses Donald Trump's tax plan with Robert Reich, Marina Franklin and Mike Yard.

Donald Trump faces fraud allegations from students of Trump University, and Larry discusses Russia's bombing campaign in Syria with Eddie Huang, Lisa Ling and Jordan Carlos.

Larry revisits his interview with presidential hopeful Bernie Sanders, and Rory Albanese, Mike Yard and Ashleigh Banfield weigh in on a mass shooting at an Oregon college.

Larry examines Hillary Clinton's public image, and Jessica Kirson, John Avlon and Joey Bada$$ talk about what qualities appeal to them in a presidential candidate.

California enacts a landmark death-with-dignity law, and Jay Leno, Bobby Gaylor and Michelle Collins discuss Ben Carson's surprising reaction to a mass shooting.

President Obama apologizes after American forces bomb a Doctors Without Borders hospital, and Rupert Murdoch tweets his support of Ben Carson's presidential campaign.

Nancy Pelosi joins Larry for an enlightening ice cream social, and Mike Yard, James Davis and Jeezy debate Barack Obama's legacy as America's first black president.

A toy pirate ship comes with a slave figurine, and Larry chats about the popularity of Donald Trump and Bernie Sanders with Jesse Ventura, Seaton Smith and Kathleen Madigan.

Larry examines the highs and lows of the first 2016 Democratic presidential debate with Steve Kornacki, Rory Albanese and Gabrielle Union.

Police officers gripe about being filmed by the public, and Larry discusses Jennifer Lawrence's essay on the gender pay gap with Grace Parra, Raul De Molina and Holly Walker.

Donald Trump spars with Jeb Bush over 9/11, Larry discusses Operation GroupMe with Raury, Mike Yard and Natasha Rothwell, and Raury performs a song from "All We Need."

American toddlers shoot people on a weekly basis, and Larry discusses wealth therapy for the beleaguered rich with Jeff Daniels, Rachel Feinstein and Joe Budden.

The CIA chief falls prey to hackers, and Larry discusses Joe Biden's announcement that he won't be running for president with Holly Walker, Ryan Duffy and Terry Crews.

A rash of fires plague black churches in Ferguson, Mo., and Larry discusses Rep. Paul Ryan's family leave demands with Lucy Lawless, Bonnie McFarlane and Judah Friedlander.

GOP presidential hopeful Rand Paul chats about Donald Trump over soul food, and Bob Saget, Ana Kasparian and Mike Yard discuss cringe-worthy Halloween costumes.

Republicans try to seize control of the presidential debates, and Larry discusses Ben Carson's unlikely political success with Ron Perlman, Crystal Wright and Jordan Carlos.

Ohio citizens vote against legalizing marijuana, and Larry discusses the clash between religion and science with Neil deGrasse Tyson, Tom Papa and Carl Lentz.

GOP presidential candidate Ben Carson releases a cringeworthy rap song, and Larry examines celebrity activism with Lola Ogunnaike, Niecy Nash and Bobby Gaylor.

Ricky Velez takes on racism in wrestling, and Larry discusses a study that claims all women are either bisexual or gay with Alex Berg, Mike Yard and Grace Parra.

Ricky Velez throws down with former WWE wrestler Virgil, and Larry discusses solutions to global warming with Bill Nye, Bridget Everett and Rory Albanese.

Shonda Rhimes discusses her memoir "Year of Yes," and Larry examines failing GOP presidential campaigns with Franchesca Ramsey, Steve Kornacki and Jordan Carlos.

A Starbucks holiday cup incurs the wrath of conservative Christians, and Larry grapples with the morals of killing baby Hitler with Norman Lear, Bill Engvall and Rick Ross.

Bernie Sanders and Hillary Clinton make waves at the second Democratic debate, and Larry discusses the term "radical Islam" with Dean Obeidallah, John Avlon and John Green.