The MPU investigates the abduction of a young child, whose abduction is likely revenge related to her father's work.

Jason, Nikki and the MPU team investigate when a woman runs down a man and forces him to get in her car at gunpoint. Meanwhile, more information about Keith's kidnapper comes to light.

The MPU searches for a college student after she goes missing during a house party. Meanwhile, Sidney and Keith try to adjust to normal life again.

The MPU works to track down the kidnapped son of a doctor, but the case takes a turn when his mother gets in direct contact with the kidnapper. Meanwhile, Kemi expresses her concerns for Sidney's wellbeing to Nikki and Jason.

A foster care worker is reported as missing, but after he ends his own life, the MPU starts to investigate a pregnant woman he was seen with who has been missing for two years. Meanwhile, Sidney follows Keith and fears he may be dangerous.

Jason and Mike search the Allegheny Mountains to find a missing couple. Meanwhile, Keith joins a trauma therapy group and bonds with another patient.

Jason and Nikki utilize a twin sister when a missing person case turns into a possible murder investigation. Meanwhile, Kemi helps C with his dating life and Keith gets reckless.

Sidney, upset that Jason and Nikki don't believe her claims about Keith, comes clean about the details surrounding the day of his disappearance, causing Jason to cast serious doubt on the boy claiming to be his son. Meanwhile, Mike's police mentor brings a missing officer's case to the MPU team.

When a bride goes missing on her wedding day, Mike and Kemi discover the woman was living a deceptive life. Meanwhile, the mystery surrounding Keith's disappearance starts to unravel as he tells Jason and Nikki more details about his time in captivity and leads them to a cabin where they find a horrifying scene.

As the MPU moves into new offices, which comes with new boss Inspector Hollis Braun, a call comes in reporting the disappearance of an entire city bus full of students on a field trip. The team utilizes a father who tried to stop the kidnapping, as Jason reaches out to an old colleague for assistance in the search.

The MPU searches for a Benjamin Franklin aficionado after he suspiciously disappears during one of his city tours. Meanwhile, a new forensic scientist is hired and the team attempts to manage her over-eager working style. Jason and Mike try to bond as new partners.

A young pregnant woman goes missing one day before her emergency c-section and the adopting mother turns to the MPU to locate her before the baby's life is risked. Meanwhile Jason digs deeper in the car bombing case and meets a disapproving Braun.

The MPU searches for a homeless female teen that disappeared after running away from home and living in Philly's Gayborhood. Kemi is hit especially hard as the team races to find and rescue the missing teen. Jason and Nikki spar over his continued investigation into the car bombing.

The MPU searches for a kidnapped tough-as-nails neighborhood watch captain. Jason enlists Wayne's help investigating the car bombing. Mike is concerned Nikki is keeping secrets from him.

Mike is taken back to his first unsolved case when the remains of an Amish man surface seven years after his murder. After he reconnects with the man's family, the wife of the man mysteriously goes missing, prompting a massive search and disclosing a web of deceit.

A popular travel influencer goes missing and the MPU race to find her as a hurricane rages and a state of emergency is declared. Mike and Wayne get closer as Helen connects with someone unexpectedly in the aftermath of Nikki's bachelorette party.

The MPU is on the case when a young hockey player goes missing during a fight with an opponent on the ice. Kemi is unexpectedly reunited with a face from the past. Nikki runs interference with Braun when Jason dives deeper into the car bombing murders.

The MPU is on the case when a young boy claims his father was abducted by aliens as they were stargazing at a remote campsite. Jason and Nikki enlist Mike's help in getting access to Braun's computer files. Kemi and Helen partner up and venture out into the field.

When Wayne goes missing on the day of Nikki & Mike's wedding, the joyous festivities are put on hold as Jason and the MPU race to locate her and finally bring down Inspector Braun and his connection to the car bombing murders.