The Orb Union space colony, Heliopolis, is attacked by ZAFT, despite its neutrality since the beginning of the Bloody Valentine War. Kira Yamato accidentally sees the Earth Alliance's new prototype mobile suits, which have been secretly constructed at the Heliopolis Morgenroete factory. He encounters his childhood friend, Athrun Zala, now a ZAFT soldier as one of the attackers.

ZAFT is able to steal four of the five G-Project prototype mobile suits, leaving only the GAT-X105 Strike. With Murrue Ramius unable to pilot it effectively, Kira pilots the Strike and defends Heliopolis against the invading ZAFT forces to protect his friends. Ensign Natarle Badgiruel takes command of the new mobile assault ship Archangel with the surviving crew members.

Lt. Murrue Ramius takes over as captain of the Archangel and Kira and his friends are detained for seeing top secret military weapons. Rau Le Creuset is determined to capture the Strike after seeing how well it moved and sends out mobile suits to retrieve it. Disobeying orders, Athrun also dispatches so he could confirm if Kira is the one piloting the Strike, but when he finds his answer, Heliopolis crumbles as it sustains too much damage.

Kira discovers a malfunctioning lifeboat and brings it aboard the Archangel. Everyone is surprised to find Flay Allster as one of the rescued civilians. The Archangel decides to head for the Eurasian Federation military satellite Artemis to seek help. Rau Le Creuset follows and plans an attack on the Archangel. Kira decides to continue piloting the Strike and his friends volunteer to become members of the Archangel crew as his support.

Mu La Flaga and Kira launch a counteroffensive against the ZAFT ship Vesalius. The Strike's Phase Shift Armor runs out of power in the middle of the battle and Athrun uses this moment to grab the Strike so he can take Kira with him, but Kira frees himself with Mu's help.

The Archangel and its crew are held captive by the Artemis forces. Nicol Amalfi in his GAT-X207 Blitz attacks Artemis, using its Mirage Colloid armor to remain effectively invisible and destroys the Umbrella of Artemis, which protects the asteroid fortress. During the attack, the Archangel is able to escape.

The Archangel forages for water in the Debris Belt. They are shocked to find themselves in the ruins of Junius Seven, so the crew decides to hold a memorial. As they are excavating ice found around the ruin, a ZAFT mobile suit attacks, but Kira dispatches him. Kira finds a floating lifepod and takes it aboard.

Lacus Clyne, the daughter of PLANT Supreme Council Chairman Siegel Clyne, is found within the lifepod. Her presence causes tension within the crew, but when the crew receives a message from the 8th Fleet that they are being searched and rescued, they are overjoyed.

The Archangel is to meet with the 8th fleet but is attacked by the Le Creuset Team. Flay witnesses the death of her father when Kira fails to protect the escort ships. In desperation, the Archangel reveals Lacus is on board the ship, causing the attackers to withdraw.

With everything that has happened, Kira becomes depressed. He is comforted by Lacus, who is strolling around the ship without permission. Kira returns Lacus to Athrun against orders, but refuses Athrun's invitation to change sides.

Le Creuset launches an attack on the Archangel. Kira's desire to protect his friends awakens an unknown almost berserker ability. He single-handedly defeats the attacking GAT-X207 Blitz, GAT-X103 Buster, and GAT-X102 Duel.

Kira and his friends are given permission to leave the Archangel, but after overcoming the initial shock of her father's death, Flay decides to enlist in the Earth Alliance Forces, prompting Sai Argyle, Kuzzey Buskirk, Miriallia Haw, and Tolle Koenig to do the same. Kira stays on board the as well to continue protecting his friends. The Duel is upgraded with an Assault Shroud.

Le Creuset attacks once again as the Archangel and the 8th Fleet approaches Earth. The Archangel is able to descend to Earth, but not without the loss of the entire 8th Fleet. Yzak Joule, the pilot of the Duel, vents his frustration by destroying a spacecraft carrying Heliopolis refugees that Kira had rescued previously.

Rau Le Creuset reflects on the events that took place in episodes one to thirteen and the Coordinator's history starting from the birth of the first Coordinator, George Glenn.

The Archangel saves Kira as they enter the Earth's atmosphere. As a result, they land in ZAFT-controlled territory in the Sahara in northern Africa, far from their intended target, Alaska. Flay begins to take care of Kira and comforts him when he is tormented by the memories of the spacecraft that was destroyed in the previous battle.

The Archangel is attacked by multiple TMF/A-802 BuCUE units. Kira hastily takes off and fights the ZAFT forces, but he is unfamiliar with the desert environment. His ability to adapt amazes ZAFT's commander Andrew Waltfeld. When the Strike is about to run out of power, a resistance group comes to his aid and lures the remaining BuCUE units into an explosive trap.

Murrue Ramius thanks the resistance group for their help and agrees to be allies. The resistance group introduces themselves as the Desert Dawn who are fighting Andrew and the Lesseps. Kira once again meets with Cagalli Yula Athha, the mysterious young woman he first encountered at Heliopolis' Morgenroete factory, who is now part of Desert Dawn. Meanwhile, Andrew attacks the Desert Dawn's hometown, but evacuates the town first.

Though the Desert Tiger has spared the lives of civilians, Desert Dawn members brashly challenge the ZAFT forces, because of the devastation they caused. The attack ends in failure, but most are saved by Kira in the Strike.

Kira and Cagalli are sent into a nearby ZAFT controlled city to gather supplies with Natarle and the Desert Dawn. The two teenagers get caught in an attack by the Blue Cosmos, and when Kira saves a man who happens to be Andrew Waltfeld, they are invited to the ZAFT base. There, Andrew reveals that he knows Kira is the pilot of the Strike and a Coordinator, but lets them leave safely.

Athrun and Nicol are given the day off; Athrun spends the day with Lacus and they talk about Kira. The PLANT Supreme Council debates on whether the attack codenamed "Operation Spitbreak" should be executed

A battle between the Lesseps and the Desert Dawn commences. Kira and the Desert Tiger fight a battle where they realize the pain of having an enemy who is not an abstraction. With the Strike's power almost depleted, Kira has no choice but to destroy Andrew's TMF/A-803 LaGOWE or die himself.

The Archangel crew crosses the Red Sea to head towards the neutral Orb Union with Cagalli and Ledonir Kisaka on board. With the previous battle weighing heavily on him, Kira talks to Cagalli about his reasons for fighting, making Flay jealous. They are attacked by ZAFT air and underwater type mobile suits, but Kira and Mu manage to take them out.

A battle with ZAFT submarine forces led by Commander Marco Morassim prevents Kira from fighting alongside Mu and Cagalli in their FX-550 Skygraspers. Cagalli's Skygrasper sustains damage and is forced to turn back, but she encounters Athrun's transport plane; her Skygrasper is shot down, but not before shooting down his transport plane, forcing Athrun in his Aegis to eject from the transport plane. By chance, they are both stranded on the same deserted island.

Cagalli is surprised to find Athrun on the same deserted island. She attacks him, but she is overpowered and captured. When everything settles down, the two discuss the war and the reason why they are fighting. At sunrise, they are rescued by their respective comrades.

The Archangel is attacked by the Zala Team which consists of the Le Creuset Team members. They take heavy damage, but when they enter the waters of the neutral nation of Orb, ZAFT is chased away and is told that the Archangel has been chased away. The Zala Team sneaks into Orb with the belief that Orb's official statement is false.

It's now C.E. 73 and three of ZAFT's newest mobile suits are stolen. During the highjacking, Cagalli, now Orb's head of state, and Athrun, now her bodyguard, are meeting with ZAFT's new head honcho.

Shinn continues to battle the three stolen suits. In the midst of battle, the three machines work to escape from Armory-1 and rendevous with their ship, Earth's "Girtty Lue", which is under the command of the mysterious Neo Roanoake.

After the Minerva launches from Armory-1, the battle against the Girty Lue ends, for the time being. However, Girty Lue launches another attack preventing the crew from having much time to regroup.

During the battle with the Girty Lue, Athrun helps the Minerva out of a bind with his strategizing.

As Junius-7 plummets towards the Earth, the Minerva team-up with the Joule team to try and destroy it.

The battle on Junius-7 instifies, as the Gaia, Chaos & Abyss make the Joule team's attempt at the destroying the falling colony much more difficult.

As a last ditch effort, the Mireva uses is Tanhäuser to break up the remaining chunk of Junius-7. Unfortunatey, several of the pieces fall to Earth destroying several of Earth's cities. The battle-damaged Minerva makes its way to Orb to re-supply and to drop Cagalli off.

The Minerva arrives at Orb. While the crew enjoys some downtime. Cagalli learns some unsettling information about the future of Orb. While Athrun decides to return to PLANT once more and meet with Dullindal.

Eager for retaliation, the Atlantic Federation declares war on ZAFT (who they blame for the Junius-7 drop). In defense of the oncoming nuclear onslaught, ZAFT unleashes its newest weapon, the Neutron Stampeder, against the Atlantic Federation forces.

As Athrun meets with Dullindal, the Dullindal-endorsed psedo-Lacus, Meer Campbell, rallies the citizens of the PLANT's look away from war and look towards peace. Later, Dullindal offers Athrun a chance to pilot one of ZAFT's newest mobile suits, the ZGMF-X23S Saviour.

Orb decides to ally itself with the Atlantic Federation, much to Cagalli's dismay. While about the PLANT's, Athrun recieves some help making his decision from some old comrades.

After departing Orb, the Minerva is thrown into battle against an Atlantic Federation fleet. Due to their new alliance with the Federation, Orb quickly sets up a baracade of ships preventing the Minerva from retreat back to the safety of Orb territory.

As the Minerva's crew congratulates Shinn on his job well done, Kira is forced to take the Freedom out into battle once again to take out the assassins that are after Lacus.

Kira, Lacus, and the remaining Archangel crew embark on their old vessel and depart, but not before Kira rescues Cagalli from her wedding to Yuna.

Athrun, now a member of the super elite ZAFT task force FAITH, returns to the Minerva. Once aboard, he delivers the Minerva's new mission to Talia.

The Minerva engages Neo and the 3 stolen Mobile Suits in a battle over the Indian Ocean.

The Minerva lands at ZAFT's Muhamal base and gets details on their next assignment. Later, Athrun has a "heart-to-heart" conversation with Shinn.

The Minerva must destroy a fixed positron cannon emplacement to break through to Gibraltar. Though hesitant at first after meeting Shinn, they are helped by a young resistance fighter named Coniel, who provides data of a secret tunnel that will lead near the positron cannon. The Minerva and the other ZAFT forces draw out the Earth Alliance mobile suits and mobile armor while Shinn heads through the tunnel and destroys the cannon.

Shinn narrates flashbacks covering the events that have transpired in Gundam SEED and SEED Destiny. He also sheds some light on how he got to the PLANT's after his tragic loss in Orb.

After a misunderstanding between Athrun, Lunamaria and Meer, Shinn takes advantage of his shore leave by exploring the countryside. On his travels he stumbles across Stellar dancing on a cliff, she then accidentally falls into the sea. Shinn dives in after her. While waiting to be rescued, Shinn and Stellar share some bonding time.

An EA fleet led by Orb forces heads towards to Black Sea to deal a critical blow to ZAFT. However, a third party is waiting in the wings to stop the battle.

Cagalli's attempts to stop the Orb fleet fails and a battle between the Minerva, Orb/EA fleet and the Archangel breaks out.

With Milliaria's help, Athrun is able to meet up with Kira and Cagalli to discuss recent events.

With Milliaria's help, Athrun is able to meet up with Kira and Cagalli to discuss recent events.

Shinn rushes an injured Stella aboard the Minerva. Once aboard, he learns startling information about Stella. Elsewhere, Lacus decides to go to PLANT and scope the situation out.