The Tonight Show with Conan O'Brien kicks it off with actor/comedian Will Ferrell and musical guest Pearl Jam.

The Tonight Show with Conan O'Brien welcomes actor Tom Hanks and musical guest Green Day.

The Tonight Show with Conan O'Brien welcomes actress Julia Louis-Dreyfus, actor Bradley Cooper and musical guest Sheryl Crow.

The Tonight Show with Conan O'Brien welcomes actress Gwyneth Paltrow, The Soup host Joel McHale and musical guest John Mayer Trio.

The Tonight Show with Conan O'Brien welcomes Ryan Seacrest, comedian Patton Oswalt and musical guests Chickenfoot.

The Tonight Show with Conan O'Brien welcomes actor David Duchovny and Anna Friel. Comedian Bill Burr performs.

The Tonight Show with Conan O'Brien welcomes actor Eddie Murphy, Angela Kinsey and musical guest Bonnie Raitt & Taj Mahal.

The Tonight Show with Conan O'Brien welcomes comedian Dane Cook, Steven Ho and musical guest Rancid.

The Tonight Show welcomes comedian Norm MacDonald, comedian Jim Gaffigan and musical guest Neko Case.

The Tonight Show with Conan O'Brien welcomes actor/singer Jamie Foxx and comedian Kevin Nealon. Music performed by Jamie Foxx.

The Tonight Show with Conan O'Brien welcomes Dodgers manager Joe Torre, actor Will Arnett and musical guest Spinal Tap.

The Tonight Show with Conan O'Brien welcomes actor/writer Larry David, Lauren Conrad and musical guest Gavin Rossdale.

The Tonight Show with Conan O'Brien welcomes basketball star Kobe Bryant, actor William Shatner and musical guests Incubus.

The Tonight Show with Conan O'Brien welcomes guests Eva Mendes, Christopher Mintz-Plasse and musical guests The Dead Weather.

The Tonight Show with Conan O'Brien welcomes actor Shia LaBeouf, L.A. Lakers' coach Phil Jackson and musical guest Holly Williams. Triumph, The Insult Comic Dog makes a special report at the Bonnaroo festival.

The Tonight Show with Conan O'Brien welcomes guests Cameron Diaz, Johnny Strange and musical guest Pete Yorn.

The Tonight Show with Conan O'Brien welcomes guests Lisa Kudrow, Billy Mays & Anthony Sullivan and musical guest Elvis Costello.

The Tonight Show with Conan O'Brien welcomes guests Brandon McMillon, Kerry Washington and musical guests Wilco.

The Tonight Show with Conan O'Brien welcomes guests Bruno, Stephen Moyer and a closing performance by Cirque du Soleil Zumanity.

The Tonight Show with Conan O'Brien welcomes guests Snoop Dogg, Jerry Ferrara and musical guest Adele.

The Tonight Show with Conan O'Brien welcomes actor/game show host Howie Mandel, singer Alanis Morissette, and musical performance by Death Cab for Cutie.

The Tonight Show with Conan O'Brien welcomes as guests actor Samuel L. Jackson, actor Kevin Connolly and musical guest Andrew Bird.

The Tonight Show with Conan O'Brien welcomes as guests from the The Today Show Meredith Vieira, from Deadliest Catch Captain Andy Hillstrand and a performance by comedian Al Madrigal.

The Tonight Show with Conan O'Brien welcomes legendary TV host Larry King, actress Zooey Deschanel and musical guests Playing For Change.

The Tonight Show with Conan O'Brien welcomes comedy great Bob Newhart, from So You Think You Can Dance TV show host Cat Deeley and musical guest Ray LaMontagne.